Hello! You're looking at a policy document report on Overton

We track government policy, guidelines, think tank research, working papers and more to help our customers see the impact and influence of their work.

If you fund, produce or manage research or work to influence policy, we'd love to talk. Learn more on our homepage.

All research cited by this document

4.3 System wide response plans for pandemic influenza, focused on the continuity of public and critical services and the stability of the economy, have been adapted for COVID-19, based on the best available scientific evidence and advice. For the latest information on the current situation please refer to: www.gov.uk/guidance/wuhan-novel-coronavirus-information-for-the-public. http://www.gov.uk/guidance/wuhan-novel-coronavirus-information-for-the-public...
On page 11
4.15 We have provided UK residents and travellers with the latest information to make sure they know what to do if they experience symptoms and worked with NHS 111, NHS Direct Wales and NHS 24 in Scotland, to ensure people with symptoms are given appropriate advice. Public health advice has been widely publicised and is regularly updated at www.gov.uk/guidance/wuhan-novel-coronavirusinformation-for-the-public http://www.gov.uk/guidance/wuhan-novel-coronavirus-information-for-the-public...
On page 13
4.55 The UK Government is advising businesses to build their own resilience by reviewing their business continuity plans and following the advice for employers available on GOV.UK - www.gov.uk/government/publications/guidance-toemployers-and-businesses-about-covid-19 http://www.gov.uk/government/publications/guidance-to-employers-and-businesses-about-covid-19...
On page 20
2.5 As it is a new virus, the lack of immunity in the population (and the absence as yet of an effective vaccine) means that COVID-19 has the potential to spread extensively. The current data seem to show that we are all susceptible to catching this disease, and thus it also more likely than not that the UK will be significantly affected. Among those who become infected, some will exhibit no symptoms 1 . Early data suggest that of those who develop an illness, the great majority 2 will have a mild-to-moderate, but self-limiting illness – similar to seasonal flu 3 ....
On page 5
1 Chan JF-W, Yuan S, Kok K-H, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020; 395: 514–23
2.5 As it is a new virus, the lack of immunity in the population (and the absence as yet of an effective vaccine) means that COVID-19 has the potential to spread extensively. The current data seem to show that we are all susceptible to catching this disease, and thus it also more likely than not that the UK will be significantly affected. Among those who become infected, some will exhibit no symptoms 1 . Early data suggest that of those who develop an illness, the great majority 2 will have a mild-to-moderate, but self-limiting illness – similar to seasonal flu 3 ....
On page 5
3 Xu XW, Wu XX, Jiang XG, Xu KJ, Ying LJ, Ma CL, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ. 2020 Feb 19;368
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
4 Sun K, Chen J, Viboud C. Early epidemiological analysis of the coronavirus disease 2019 outbreak based on crowdsourced data: a population-level observational study. Lancet Digital Health 2020; published online Feb 20. https://doi.org/10.1016/S2589-7500(20)30026-1
Science China Life Sciences (Springer Science and Business Media LLC)
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
5 Liu Y, Yang Y, Zhang C, Huang F, Wang F, Yuan J, et al. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Science China Life Sciences. 2020 Feb 9:1-1
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
6 Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet. 2020 Jan 30
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
7 Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020 Jan 24
New England Journal of Medicine (Massachusetts Medical Society)
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
9 Li, Q., et al Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus- Infected Pneumonia. NEJM. 2020 Jan 29 DOI: 10.1056/NEJMoa2001316
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
11 Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, Li J, Zhao D, Xu D, Gong Q, Liao J. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet. 2020 Feb 12
2.6 It is, however, also clear that a minority of people who get COVID-19 will develop complications severe enough to require hospital care 4 , most often pneumonia. In a small proportion of these, the illness may be severe enough to lead to death 5 . So far the data we have suggest that the risk of severe disease and death increases amongst elderly people and in people with underlying health risk conditions (in the same way as for seasonal flu) 6 7 . Illness is less common and usually less severe in younger adults 8 . Children can be infected 9 and can have a severe illness 10 , but based on current data overall illness seems rarer in people under 20 years of age. So far, there has been no obvious sign that pregnant women are more likely to be seriously affected 11 12 ....
On page 5
12 Qiao J. What are the risks of COVID-19 infection in pregnant women?. The Lancet. 2020 Feb 12
3.2 The UK is well prepared for disease outbreaks, having responded to a wide range of infectious disease outbreaks in the recent past, and having undertaken significant preparedness work for an influenza pandemic for well over one decade (eg. our existing plan ‘flu plans 16 ). Our plans have been regularly tested and updated locally and nationally to ensure they are fit for purpose. This experience...
On page 8
16 https://www.gov.uk/government/publications/Responding-to-a-uk-flu-pandemic
4.1 There is similarity between COVID-19 and influenza (both are respiratory infections), but also some important differences. Consequently, contingency plans developed for pandemic influenza 17 , and lessons learned from previous outbreaks, provide a useful starting point for the development of an effective response plan to COVID-19. That plan has been adapted, however, to take account of differences between the two diseases. Annex A sets out the structure for the UK’s response to a disease outbreak....
On page 11
17 https://www.gov.uk/government/publications/Responding-to-a-uk-flu-pandemic