Policy document
June 18th 2019

Test No. 203: Fish, Acute Toxicity Test

Flag of IGO IGO
OECD
OECD
https://www.oecd.org Flag of igo IGO

The Organisation for Economic Co-operation and Development is an intergovernmental organization with 38 member countries, founded in 1961 to stimulate economic progress and world trade. It is a forum the members of which are countries describing themselves as committed to democracy and the market economy, providing a platform to compare policy experiences, seek answers to common problems, identify good practices and coordinate domestic and international policies of its members. The majority of OECD members are high-income economies with a very high Human Development Index (HDI) and are regarded as developed countries.
The fish are exposed to the test substance preferably for a period of 96 hours. Mortalities are recorded at 24, 48, 72 and 96 hours and the concentrations which kill 50 per cent of the fish (LC50) are determined where possible. One or more species may be used, the choice being at the discretion of the testing laboratory. At least seven fishes must be used at each test concentration and in the controls. The test substance should be administered to, at least, five concentrations in a geometric series with a factor preferably not exceeding 2.2. The limit test corresponds to one dose level of 100 mg/L. This study includes the observations of fish at least after 24, 48, 72 and 96 hours. The cumulative percentage mortality for each exposure period is plotted against concentration on logarithmic probability paper.

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Identifiers

Overton ID
oecddiscovery-0d9d59fe49ecbac0c0e586657f2cc0dd
doi
10.1787/9789264069961-en

Topics in this document

Aquatic toxicology Water PH Probit Total organic carbon Validity (statistics) Physical sciences Chemistry Toxicity Chronic toxicity Solvent Water quality Chemical substance Dissolved organic carbon Statistics Solution (chemistry) Biocide Alternatives to animal testing Fathead minnow Silicone Solubility Median lethal dose OECD Breathing Chemical oxygen demand Purified water Toxicology Likelihood function

Related COFOG Divisions

5: Environmental Protection 5.3: Pollution Abatement 7: Health 7.5: R&D Health

Citations

Cited by 74 other policy documents (59 of them are from other policy sources)