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Identifiers

Overton ID
oecddiscovery-21d4c7749f8a411f60c869413f4dc542
doi
10.1787/9789264069725-en

Test No. 112: Dissociation Constants in Water

Flag for IGO OECD on May 12th 1981
This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation constant requires a measure of the concentrations of the dissociated and undissociated forms of the chemical substance. From a knowledge of the stoichiometry of the dissociation reaction the appropriate constant can be determined. In the particular case described in this Guideline the substance is behaving as an acid or a base, and the determination is most conveniently done by determining the relative concentrations of ionised and unionised forms of the substance and the pH of the solution. The relationship between these terms is given in the equation for pKa. Some compounds exhibit more than one dissociation constant. Some of the methods described are also suitable for non-acid/base dissociation. There are two basic approaches to the determination of pKa. One inv...

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Related SDGs

SDG 6: Clean Water and Sanitation ...
SDG 6: Clean Water and Sanitation

Target 6.3

Improve water quality by reducing pollution, eliminating dumping and minimizing release of hazardous chemicals and materials, halving the proportion of untreated wastewater and substantially increasing recycling and safe reuse globally

Citations

Cited by 13 other policy documents (9 of them are from other policy sources)