Hello! You're looking at a policy document report on Overton
We track government policy, guidelines, think tank research, working papers and more to help our customers see the impact and influence of their work. Are you interested in seeing what information we have to offer? Request a free trial to our platform.
If you fund, produce or manage research or work to influence policy, we'd love to talk. Learn more on our homepage.
Identifiers
Amantadine and rimantadine for influenza A in adults
Guidelines in PubMed Central
on
April 19th 2006
The Cochrane Database of Systematic Reviews
Abstract Background Amantadine hydrochloride (amantadine) and rimantadine hydrochloride (rimantadine) have antiviral properties, but they are not widely used due to a lack of knowledge of their potential value and concerns about possible adverse effects. This review was first published in 1999 and updated for the fourth time in April 2008. Objectives The objective of this review was to assess the efficacy, effectiveness and safety ('effects') of amantadine and rimantadine in healthy adults. Search methods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2008, issue 1), MEDLINE (1966 to April Week 4, 2008), EMBASE (1990 to April 2008) and reference lists of articles. Selection criteria Randomised and quasi‐randomised studies comparing amantadine and/or rimantadine with placebo, control medication or no intervention, or comparing doses or schedules of amantadine and/or rimantadine in healthy adults. Data collection and analysis For prophylaxis (prevention) tria...
Topics in this document
Medicine
Randomized controlled trial
Influenza
Amantadine
Systematic review
Vaccine efficacy
Cochrane (organisation)
Blinded experiment
Placebo
Rimantadine
Confidence interval
Influenza A virus subtype H1N1
Influenza A virus subtype H3N2
Placebo-controlled study
Adverse effect
Meta-analysis
Antiviral drug
Influenza vaccine
Health sciences
Medical specialties
Health
Clinical medicine
Health care
Preventive healthcare
Clinical trial
Diseases and disorders
Public health
Infection
Allocation concealment
Risk
Related SDGs
Citations
Cited by 11
other policy documents
(7 of them are from other policy sources)