Hello! You're looking at a policy document report on Overton

We track government policy, guidelines, think tank research, working papers and more to help our customers see the impact and influence of their work.

If you fund, produce or manage research or work to influence policy, we'd love to talk. Learn more on our homepage.

Everything cited by this document (explore the cited scholarly articles) (explore the cited policy documents)

Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
M T Brady et al. 1990
Brady MT, Sears SD, Pacini DL, Samorodin R, DePamphilis J, Oakes M, et al. Safety and prophylactic efficacy of lowdose rimantadine in adults during an influenza A epidemic Antimicrobial. Agents and Chemotherapy 1990;34:1633-66.
The Journal of Clinical Pharmacology and The Journal of New Drugs (Wiley)
EINAR CALLMANDER et al. 1968
Callmander E, Hellgren L. Amantadine hydrochloride as a prophylactic in respiratory infections. A double-blind investigation of its clinical use and serology. Journal of Clinical Pharmacology 1968;8:186-9.
New England Journal of Medicine (New England Journal of Medicine (NEJM/MMS))
Raphael Dolin et al. 1982
Dolin R, Reichman RC, Madore HP, Maynard R, Linton PN, Webber-Jones J. A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection. New England Journal of Medicine 1982;307:580-4.
Galbraith AW, Oxford JS, Schild GC, Potter CW, Watson GI. Therapeutic effect of 1-adamantanamine hydrochloride in naturally occurring influenza A 2/Hong Kong infection - a controlled double-blind study. Lancet 1971;2:113-5.
Journal of Infectious Diseases (Oxford University Press (OUP))
F. G. Hayden et al. 1980
Hayden FG, Hall WJ, Douglas RG. Therapeutic effects of aerosolized amantadine in naturally acquired infection due to influenza A virus. Journal of Infectious Diseases 1980;141:535-42.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
F G Hayden et al. 1981
Hayden FG, Gwaltney JM, van de Castle RL, Adams KF, Giordani B. Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults. Antimicrobial Agents and Chemotherapy 1981;19:226-33.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
F G Hayden et al. 1986
Hayden FG, Monto AS. Oral rimantadine hydrochloride therapy of influenza A virus H3 N2 subtype infection in adults. Antimicrobial Agents and Chemotherapy 1986;29:339-41.
Hornick RB, Togo Y, Mahler S, Iezzoni D. Evaluation of amantadine hydrochloride in the treatment of A2 influenzal disease. Bulletin of the World Health Organization 1969;41:671-6.
Hornick RB, Togo Y, Mahler S, Iezzoni D. Evaluation of amantadine hydrochloride in the treatment of A2 influenzal disease. Bulletin of the World Health Organization 1969;41:671-6.
Hornick RB, Togo Y, Mahler S, Iezzoni D. Evaluation of amantadine hydrochloride in the treatment of A2 influenzal disease. Bulletin of the World Health Organization 1969;41:671-6.
Hornick RB, Togo Y, Mahler S, Iezzoni D. Evaluation of amantadine hydrochloride in the treatment of A2 influenzal disease. Bulletin of the World Health Organization 1969;41(Trial no AMANT18):671-6.
Kantor RJ, Potts DW, Stevens D, Noble GR. Prevention of influenza A/USSR/77 (H1N1): an evaluation of the side effects and efficacy of amantadine in recruits at Fort Sam Houston. Military Medicine 1980;145:312-5.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
V M Millet et al. 1982
Millet VM, Dreisbach M, Bryson YJ. Double-blind controlled study of central nervous system side effects of amantadine, rimantadine and chlorpheniramine. Antimicrobial Agents and Chemotherapy 1982;21(1):1-4.
JAMA: The Journal of the American Medical Association (American Medical Association (AMA))
A. S. Monto 1979
Monto AS, Gunn RA, Bandyk MG, King CL. Prevention of Russian influenza by amantadine. Journal of the American Medical Association 1979;241:1003-7.
Nafta I, Turcanu AG, Braun I, Companetz W, Simionescu A, Birţ E, et al. Administration of amantadine for the prevention of Hong Kong influenza. Bulletin of the World Health Organization 1970;42(3):423-7.
Oker-Blom N, Hovi T, Leinikki P, Palosuo T, Pettersson R, Suni J. Protection of man from natural infection with influenza A2 Hong Kong virus by amantadine: a controlled field trial. British Medical Journal 1970;3:676-8.
The Lancet (Elsevier BV)
D.K. Payler et al. 1984
Payler DK, Purdham PA. Influenza A prophylaxis with amantadine in a boarding school. Lancet 1984;1:502-4.
Annals of the New York Academy of Sciences (Wiley)
Robert O. Peckinpaugh et al. 1970
Peckinpaugh RO, Askin FB, Pierce WE, Edwards EA, Johnson DP, Jackson GG. Field studies with amantadine: acceptability and protection. AMANTADINE 42. Annals of the New York Academy of Sciences 1970;173:62-73.
Peckinpaugh RO, Askin FB, Pierce WE, Edwards EA, Johnson DP, Jackson GG. Field studies with amantadine: acceptability and protection. AMANTADINE 42. Annals of the New York Academy of Sciences 1970;173:62-73.
Pettersson RF, Hellstrom PE, Penttinen K, Pyhala R, Tokola O, Vartio T, et al. Evaluation of amantadine in the prophylaxis of influenza A (H1N1) virus infection: a controlled field trial among young adults and high-risk patients. Journal of Infectious Diseases 1980;142:377-83.
Antiviral Research (Elsevier BV)
John M. Quarles et al. 1981
Quarles JM, Couch RB, Cate TR, Goswick CB. Comparison of amantadine and rimantadine for prevention of type A (Russian) influenza. Antiviral Research 1981;1:149-55.
The American Journal of the Medical Sciences (Elsevier BV)
S. Rabinovich et al. 1969
Rabinovich S, Baldini JT, Bannister R. Treatment of influenza. The therapeutic efficacy of rimantadine HC1 in a naturally occurring influenza A2 outbreak. The American Journal of the Medical Sciences 1969;257(5):328-35.
Antiviral Research (Elsevier BV)
Peter D. Reuman et al. 1989
Reuman PD, Bernstein DI, Keefer MC, Young EC, Sherwood JR, Schiff GM. Efficacy and safety of low dosage amantadine hydrochloride as prophylaxis for influenza A. Antiviral Research 1989;11:27-40.
Smorodintsev AA, Karpuhin GI, Zlydnikov DM, Malyseva AM, Svecova EG, Burov SA, et al. The prophylactic effectiveness of amantadine hydrochloride in an epidemic of Hong Kong influenza in Leningrad in 1969. Bulletin of the World Health Organization 1970;42:865-72.
JAMA: The Journal of the American Medical Association (American Medical Association (AMA))
L. P. Van Voris 1981
van Voris LP, Betts RF, Hayden FG, Christmas WA, Douglas RG. Successful treatment of naturally occurring influenza A/ USSR/77 H1N1. Journal of the American Medical Association 1981;245:1128-31.
Clinical Pharmacology & Therapeutics (Wiley)
Herbert A. Wendel et al. 1966
Wendel HA, Snyder MT, Pell S. Trial of amantadine in epidemic influenza. Clinical Pharmacology and Therapeutics 1966;7:38-43.
New England Journal of Medicine (Massachusetts Medical Society)
W. L. Wingfield et al. 1969
Wingfield WL, Pollack D, Grunert RR. Therapeutic efficacy of amantadine HC1 and rimantadine HC1 in naturally occurring influenza A2 respiratory illness in man. New England Journal of Medicine 1969;281:579-84.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
S W Younkin et al. 1983
Younkin SW, Betts RF, Roth FK, Douglas RG. Reduction in fever and symptoms in young adults with influenza A/Brazil/78 H1N1 infection after treatment with aspirin or amantadine. Antimicrobial Agents and Chemotherapy 1983;23:577-82.
Aoki FY, Stiver HG, Sitar DS, Hammond GW, Milley EV, Vermeersch C, et al. Potential of influenza vaccine and amantadine to prevent influenza A illness in Canadian forces personnel 1980-1983. Military Medicine 1986;151:459-65.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
R L Atmar et al. 1990
Atmar RL, Greenberg SB, Quarles JM, Wilson SZ, Tyler B, Feldman S, et al. Safety and pharmacokinetics of rimantadine small-particle aerosol. Antimicrobial Agents and Chemotherapy 1990;34:2228-33.
Bryson YJ, Monahan C, Pollack M, Shields WD. A prospective double-blind study of side effects associated with the administration of amantadine for influenza A virus prophylaxis. Journal of Infectious Diseases 1980;141:543-7.
Archives of Pediatrics & Adolescent Medicine (American Medical Association (AMA))
Richard D. Clover 1986
Clover RD, Crawford SA, Abell TD, et al. Effectiveness of rimantadine prophylaxis of children within families. American Journal of Diseases of Children 1986;140:706-9.
The Pediatric Infectious Disease Journal (Ovid Technologies (Wolters Kluwer Health))
STEVEN A. CRAWFORD et al. 1988
Crawford SA, Clover RD, Abell TD, Ramsey CN, Glezen WP, Couch RB. Rimantadine prophylaxis in children: a follow-up study. Pediatric Infectious Disease Journal 1988;7:379-83.
JAMA (American Medical Association (AMA))
Albert T. Dawkins 1968
Dawkins AT Jr, Gallager LR, Togo Y, Hornick RB, Harris BA. Studies on induced influenza in man. II. Double-blind study designed to assess the prophylactic efficacy of an analogue of amantadine hydrochloride. JAMA 1968;203(13):1095-9.
American Journal of Epidemiology (Oxford University Press (OUP))
JOHN F. FINKLEA et al. 1967
Finklea JF, Hennessy AV, Davenport FM. A field trial of amantadine prophylaxis in naturally-occurring acute respiratory illness. American Journal of Epidemiology 1967;85(3):403-12.
Galbraith AW, Oxford JS, Schild GC, Watson GI. Study of 1- adamantanamine hydrochloride used prophylactically during the Hong Kong influenza epidemic in the family environment. Bulletin of the World Health Organization 1969;41:677-82.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
F G Hayden et al. 1983
Hayden FG, Hoffman HE, Spyker DA. Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics. Antimicrobial Agents and Chemotherapy 1983;231(3):458-64.
Antimicrobial Agents and Chemotherapy (American Society for Microbiology)
F G Hayden et al. 1985
Hayden FG, Minocha A, Spyker DA, Hoffman HE. Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults. Antimicrobial Agents and Chemotherapy 1985;28(2):216-21.
New England Journal of Medicine (Massachusetts Medical Society)
Frederick G. Hayden et al. 1989
Hayden FG, Belshe RB, Clover RD, Hay AJ, Oakes MG, Soo W. Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. New England Journal of Medicine 1989;321:1696-702. use of rimantadine. Antimicrobial Agents and Chemotherapy 1991;35:1741-7.
American Journal of Epidemiology (Oxford University Press (OUP))
J. MORGAN O'DONOGHUE et al. 1973
O'Donoghue JM, Ray CG, Terry DW, Beaty HN. Prevention of nosocomial influenza infection with Amantadine. American Journal of Epidemiology 1972;97:276-82.
Smorodintsev AA, Karpuhin GI, Zlydnikov DM, Malyseva AM, Svecova EG, Burov SA, et al. The prospect of amantadine for prevention of influenza A2/Hong Kong epidemics in January- February 1969 in Leningrad. Annals of the New York Academy of Science 1970;173:44-73.
JAMA: The Journal of the American Medical Association (American Medical Association (AMA))
A. A. Smorodintsev 1970
Smorodintsev AA, Zlydnikov DM, Kiseleva AM, Romanov JA, Kazantev AP, Rumovsky VI. Evaluation of amantadine in artificially induced A2 and B influenza. JAMA 1970;213:1448-54.
JAMA (American Medical Association (AMA))
Yasushi Togo 1968
Togo Y, Hornick RB, Dawkins AT Jr. Studies on induced influenza in man. I. Double-blind studies designed to assess prophylactic efficacy of amantadine hydrochloride against a2/Rockville/1/65 strain. JAMA 1968;203(13):1089-94.
JAMA: The Journal of the American Medical Association (American Medical Association (AMA))
Yasushi Togo 1970
Togo Y, Hornick RB, Felitti VJ, Kaufman ML, Dawkins AT, Kilpe VE, et al. Evaluation of therapeutic efficacy of amantadine in patients with naturally occurring A2 influenza. JAMA 1970;211:1149-56.
Bright RA, Medina MJ, Xu X, Perez-Oronoz G, Wallis TR, Davis XM, et al. Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet 2005;366:1175-81.
Controlled Clinical Trials (Elsevier BV)
Rebecca DerSimonian et al. 1986
DerSimonian R, Laird N. Meta-analysis in clinical trials. Controlled Clinical Trials 1986;7:177-88.
JAMA (American Medical Association (AMA))
Kenneth F. Schulz 1995
Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 1995;273:408-12.
The Lancet (Elsevier BV)
T Jefferson et al. 2006
Jefferson T, Demicheli V, Rivetti D, Jones M, Di Pietrantonj C, Rivetti A. Antivirals for influenza in healthy adults: systematic review. The Lancet 2006;367(9507):303-13. [DOI: 10.1016/ S0140-6736(06) 67970-1.]