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Identifiers

Overton ID
pubmedcentral-624d1a22e79f0c9706d5edaa79dc15c0
doi
10.1002/14651858.cd008242.pub3

Amitriptyline for neuropathic pain in adults

Flag for USA Guidelines in PubMed Central on July 6th 2015
The Cochrane Database of Systematic Reviews
Abstract Background This is an updated version of the original Cochrane review published in Issue 12, 2012. That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with in a separate review. Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to nerve damage). It is recommended as a first line treatment in many guidelines. Neuropathic pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants. Objectives To assess the analgesic efficacy of amitriptyline for relief of chronic neuropathic pain, and the adverse events associated with its use in clinical trials. Search methods We searched CENTRAL, MEDLINE, and EMBASE to March 2015, together with two clinical trial registries, and the reference lists of retrieved papers, previous systematic reviews, and other reviews; we also used our own hand searched database for older studies. Selecti...

Topics in this document

Related SDGs

SDG 3: Good Health and Well-being ...
SDG 3: Good Health and Well-being

Target 3.4

Reduce by one third premature mortality from non-communicable diseases through prevention and treatment and promote mental health and well-being

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Citations

Cited by 47 other policy documents (24 of them are from other policy sources)
 

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