Policy document
August 1st 2014

Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults

Flag of USA USA
Guidelines in PubMed Central
Guidelines in PubMed Central
https://www.ncbi.nlm.nih.gov Flag of usa USA

This source collects the practice and clinical guidelines published in journals worldwide that are available on PubMed Central, an open repository of biomedical research run by the National Institutes of Health in the USA.
The Cochrane database of systematic reviews
Background Migraine is a common, disabling condition and a burden for the individual, health services and society. Many sufferers choose not to, or are unable to, seek professional help and rely on over-the-counter analgesics. Co-therapy with an antiemetic should help to reduce nausea and vomiting commonly associated with migraine. Objectives To determine the efficacy and tolerability of paracetamol (acetaminophen), alone or in combination with an antiemetic, compared to placebo and other active interventions in the treatment of acute migraine in adults. Search methods We searched Cochrane CENTRAL, MEDLINE, EMBASE and the Oxford Pain Relief Database for studies through 4 October 2010. Selection criteria We included randomised, double-blind, placebo- or active-controlled studies using self-administered paracetamol to treat a migraine headache episode, with at least 10 participants per treatment arm. Data collection and analysis Two review authors independently assessed trial quality and extracted data. Numb...

Hello! You're looking at a policy document report on Overton

We track government policy, guidelines, think tank research, working papers and more to help our customers see the impact and influence of their work. Are you interested in seeing what information we have to offer?

If you fund, produce or manage research or work to influence policy, we'd love to talk.

Request a free trial Learn more

Language: eng
58 pages

Download PDF

Identifiers

Overton ID
pubmedcentral-92455230991e61dc3bb275594d1f9014
doi
10.1002/14651858.cd008040.pub2

Topics in this document

Cyclooxygenase Migraine Nonsteroidal anti-inflammatory drug COX-3 Headache Metoclopramide Medical specialties Clinical medicine Health Medicine Health sciences Health care Medical treatments Pharmacology Drugs Paracetamol Analgesic Sumatriptan Placebo Medical research Adverse effect

Related SDGs

SDG 3: Good Health and Well-being
SDG 3: Good Health and Well-being

Target 3.4

Reduce by one third premature mortality from non-communicable diseases through prevention and treatment and promote mental health and well-being

Related COFOG Divisions

7: Health 7.1: Medical Products, Appliances and Equipment

Citations

Cited by 3 other policy documents (2 of them are from other policy sources)

Recognized names mentioned in this document

Overton only tracks names from certain institutions. Names must have been cited in at least one policy document and their corresponding affiliation has to be found nearby - you can find more details on the help page.

Sheena Derry at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
Maura Moore at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
R. Andrew at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
Andrew Moore at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
R. Andrew Moore at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
Henry J McQuay at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)
R Andrew Moore at University of Oxford
This name and affiliation were mentioned in this document.
On page 1 (or quick view this section)